
Pyridoxamine dihydrochloride
CAS No. 524-36-7
Pyridoxamine dihydrochloride( Pyridorin | Pyridoxylamine Dihydrochloride )
Catalog No. M19616 CAS No. 524-36-7
Pyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.
Purity : >98% (HPLC)






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Biological Information
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Product NamePyridoxamine dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.
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DescriptionPyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.(In Vitro):Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.(In Vivo):Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
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In VitroPyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.
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In VivoPyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
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SynonymsPyridorin | Pyridoxylamine Dihydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number524-36-7
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Formula Weight241.12
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Molecular FormulaC8H14Cl2N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCl.Cl.Cc1ncc(CO)c(CN)c1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Adrover M et al. The pyridoxamine action on Amadori compounds: A reexamination of its scavenging capacity and chelating effect. Bioorg Med Chem. 2008 May 15;16(10):5557-69.
molnova catalog



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